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Pulmonary embolism (PE) is the main trigger of in-hospital death and the third most frequent cause of cardiovascular demise. The clinical presentation of PE is variable, and selecting the suitable treatment for individual patients might be difficult. Historically, treatment of PE has concerned a choice of anticoagulation, thrombolysis or surgery; however, a variety of percutaneous interventional applied sciences have been developed which might be below investigation in patients with intermediate-high-risk or excessive-risk PE. These interventional technologies include catheter-directed thrombolysis (with or without ultrasound help), aspiration thrombectomy and mixtures of the aforementioned rules. These interventional treatment choices may lead to a extra fast improvement in right ventricular operate and pulmonary and/or systemic haemodynamics specifically patients.